Limping (lameness) is one of the most common reasons dog owners seek veterinary care, and the causes span a wide spectrum. In young, active dogs, the most frequent culprits are soft tissue injuries—sprains, strains, and muscle soreness from overexertion during play or exercise. These often resolve with a few days of rest. Paw pad cuts, embedded foxtails or thorns, and broken toenails are also common and can usually be identified with a careful at-home examination of the affected limb.
More serious causes of limping include cranial cruciate ligament (CCL) tears, which are analogous to ACL tears in humans. CCL injuries are extremely common in dogs, particularly in larger breeds, and typically require surgical repair. Symptoms include sudden hind-leg lameness, reluctance to bear weight, and swelling around the knee (stifle) joint. In older dogs, limping may indicate osteoarthritis, which tends to worsen gradually over weeks to months and is often most apparent after rest.
In large and giant breed dogs, persistent limping that doesn't improve with rest should be evaluated promptly, as osteosarcoma (bone cancer) is a serious consideration, especially in the long bones of the legs. Fractures from trauma, Lyme disease, immune-mediated polyarthritis, and developmental orthopedic conditions like hip dysplasia or elbow dysplasia are additional causes your vet may investigate. Radiographs (X-rays) are the first-line diagnostic tool for evaluating most causes of lameness.